Case Reports of Cardiac

Cardiac involvement is the most important cause of death in patients with sarcoidosis, yielding a 5-year mortality risk up to 66% despite appropriate immunosuppressive treatment. Early diagnosis and prompt initiation of corticosteroid therapy in this population has proven to improve left ventricular (LV) function though, at the same time reducing risk of malignant arrhythmia. Recently, two-dimensional speckle-tracking echocardiography has been introduced as a new and highly sensitive echocardiographic technique to assess regional and global biventricular performance, detecting myocardial tissue diseases even in the pre-clinical stage. We report a histology proven case of cardiac sarcoidosis in which strain curves of each LV segment were matched to macroscopic findings of the explanted heart, with the aim to test accuracy of deformation imaging in identifying specific areas involved by myocardial infiltration/inflammation.

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