Cardiology and Cardiovascular Medicine Research

Hypertension and Cardiac Progenitors

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Hypertension (HTN or HT), also known as high blood pressure, is a long term medical condition in which the blood pressure in the arteries is persistently elevated.^[1] High blood pressure usually does not cause symptoms.^[2] Long term high blood pressure; however, is a major risk factor for coronary artery disease, stroke, heart failure, peripheral vascular disease, vision loss, and chronic kidney disease.Cardiac progenitor cells (CPCs) are committed to the cardiac lineage but retain their proliferative capacity before becoming quiescent mature cardiomyocytes (CMs). In medical therapy and research, the use of human pluripotent stem cell-derived CPCs would have several advantages compared with mature CMs, as the progenitors show better engraftment into existing heart tissues, and provide unique potential for cardiovascular developmental as well as for pharmacological studies. Cardiac progenitor cells (CPCs) represent the earliest stages of mesoderm commitment to the cardiac lineages and directed differentiation of CPCs from pluripotent stem cells has been demonstrated in a number of recent studies. Furthermore, these cells have been shown to be capable of generating other terminal cardiac cell types such as cardiomyocytes, endothelial cells, and vascular smooth muscle cells.  However, utilization of CPCs for such endeavors requires a robust, scalable, and consistent differentiation methodology.

Related Conferences

7^th World Cardiothoracic Meeting March 29-30, 2016 Atlanta, USA; Echo Cardiography Conference June 06-07, 2016 London, UK; Ischemic Heart Diseases Conference May 12-13, 2016 Chicago, USA; 8^th Global Cardiologists Annual Meeting July 18-20, 2016 Berlin, Germany; Annual Conference on Atherosclerosis July 11-12, 2016 Philadelphia, USA; Drug Discovery and Therapy World Congress May 11-14, 2016, Boston, USA; 7^th International Conference on Drug Discovery and Therapy, February 15-18, 2016 Dubai, UAE; Arrhythmias & the Heart: A Cardiovascular Update, February 12–16, 2016, Riyadh, Saudi Arabia; 16^th Annual International Symposium on Congenital Heart Disease, February 13–16, 2016, St. Petersburg, USA; Cardiovascular Conference at Snowbird, February 12-15, 2016, Snowbird, Utah; Korean Cardiology Related Societies Joint Scientific Congress, April 15-16, 2016, Daegu, Korea.